![]() Lee and his colleagues randomly assigned 127 adults – all in a 12-week clinical trial of cannabis use disorder treatment – to receive extended-release zolpidem or placebo. “Research indicates that cannabis cessation results in sleep problems that are a barrier to quitting,” Dr. Whatever the explanation, the sleep problems during withdrawal are not helpful to users who are trying to quit. “Studies have demonstrated that acute use of cannabis reduces sleep latency and increases stage 3 sleep, informally referred to as ‘deep’ or ‘slow-wave’ sleep, which means individuals fall asleep faster and remain in deep sleep longer after using cannabis,” Dr. 2010 Sep 1 111:120-7).Īnother factor could be at play: Cannabis users may sleep better while they use the drug, then lose the benefit when they try to withdraw. ![]() Nearly half reported trouble falling asleep, while 20%-36% reported sleep-related symptoms, such as sleeping more or less than usual, having unusual dreams, and waking during the night ( Drug Alcohol Depend. In a 2010 study, for instance, researchers interviewed 469 adult cannabis users in the Baltimore area who had tried to quit outside of treatment programs. Previous research, including studies by some of the authors of the new report, suggests that people trying to withdraw from cannabis often suffer from sleep disturbances. He presented the study findings at the annual meeting of the College on Problems of Drug Dependence. Lee, PhD, of Johns Hopkins University, Baltimore, said in an interview. But they should only be used in cases where abstinence-induced insomnia is a significant barrier to cessation and only in combination with other evidence-based interventions to address key aspects of cannabis use disorder,” study coauthor Dustin C. “Zolpidem or other hypnotics may have some efficacy as a pharmacotherapy to relieve short-term sleep disruption in the treatment of cannabis use disorder. ![]() And the subjects who took zolpidem were not significantly more likely to abstain from cannabis in the long term. Zolpidem seemed to help subjects sleep better, but the effect lasted only as long as they took the drug. Now, a new study provides more evidence about the problem and suggests that the sleep aid zolpidem is not a solution on its own. SAN DIEGO – Disturbed sleep is one of the symptoms of withdrawal from marijuana, and it can wreak havoc on the lives of people with cannabis use disorder who are trying to quit.
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